Investigation of the relationship of frontal QRS-T angle and digoxin use and blood digoxin level

Objectives: Digoxin is an antiarrhythmic drug with a narrow therapeutic range and used in clinical conditions such as heart failure atrial fibrillation. The planar frontal QRS-T angle reflects the deviations between depolarization repolarization of ventricles, it has been reported that increase this associated mortality. In our study, relationship digoxin use blood level was investigated. Methods: study included 105 users who digoxin, whose levels were measured, had electrocardiogram (ECG) on system, 15 patients similar characteristics, ECG did not digoxin. Patients using measured also divided into three groups < 0.8 ng/mL, 0.8-1.2 > 1.2 ng/mL. absolute value obtained by subtracting axis T wave from QRS indicated paper, calculated automatically 12-lead ECG, accepted value. Results: Planar 120º (55.5º-155.5º), while 106º (32º-163º) non-users, there no statistical difference two (p = 0.833). evaluation made according to different ng/mL users, significant observed (109.5° [60.25°-154.25°] for 136.5° [48.5°-158.5°] 117° [34°-154°] ng/mL) 0.773).Conclusions: There non-users. angle.